Polyplus-transfection® SA is a biotechnology company that develops and sells innovative solutions for the delivery of nucleic acids in research, bioproduction and therapeutics. Located close to the University of Strasbourg in Eastern France, Polyplus-transfection® is ISO 9001-certified since 2002 and supplies its wide range of reagents for the transfection of genes, oligonucleotides and siRNA through a worldwide distributor network.
Polyplus-transfection® reagents are involved in a growing number of clinical trials worldwide. In addition, Polyplus-transfection® holds a broad estate of patents and licenses including original methods for therapeutic siRNA delivery.
Products | Delivered Molecules | Cell types | Recommended use | |||||
Plasmid DNA | Oligo-nucleotides (siRNA, miRNA & others) | mRNA | Proteins, peptides & antibodies | Adherent | Suspension | Specific | ||
In vitro | ||||||||
| ✓ | ✓ | +++ | Research purpose | |||||
| ✓ | +++ | +++ | RNA interference | |||||
| ✓ | +++ | +++ | Hard to transfect cells | Research purpose | ||||
| ✓ | +++ | Suspension CHO & HEK-293 | Bioproduction | |||||
| ✓ | ++ | ++ | HEK-293 | Virus & protein bioproduction | ||||
| ✓ | ++ | ++ | HEK-293 | Production of clinical batches of proteins and viruses | ||||
| ✓ | ++ | + | High Throughput Screening Research purpose | |||||
| ✓ | +++ | Primary macrophages, glial & dendritic cells | Cell specific | |||||
| ✓ | +++ | Primary Hepatocytes | Cell specific | |||||
| ✓ | +++ | Endothelial cells | Cell specific | |||||
+++ | +++ | Proteofection | ||||||
Products | Plasmid DNA | Oligo-nucleotides | mRNA | Proteins | Adherent | Suspension | Specific | Recommended use |
In vivo | ||||||||
| ✓ | ✓ | ✓ | in vivo delivery to all organs | |||||
| ✓ | ✓ | ✓ | Therapeutic in vivo delivery to all organs | |||||
| ✓ | ✓ | ✓ | Therapeutic in vivo delivery to all organs | |||||
| ✓ | ✓ | ✓ | in vivo delivery delivery to mannose-receptor expressing tissue | |||||
| ✓ | ✓ | ✓ | in vivo delivery to liver | |||||
| ✓ | siRNA delivery to brain | |||||||
Products | Plasmid DNA | Oligo-nucleotides | mRNA | Proteins | Adherent | Suspension | Specific | Recommended use |
Other | ||||||||
Molecular Biology & Diagnostics | ||||||||
Therapeutic siRNA | ||||||||
Therapeutic cationic Oligonucleotides | ||||||||
Transfection optimization | ||||||||
in vitro transfection, therapeutics | ||||||||